Elevation of homocysteine is implicated in multiple medical conditions, including classical
homocystinuria, a variety of remethylation disorders, and most recently in coronary artery
disease. Betaine is a methyl donor agent that is beneficial in lowering homocysteine through
the remethylation of methionine. Betaine therapy alone has been shown to prevent vascular
events in homocystinuria and may have clinical benefits in other hyperhomocysteinemic
disorders when used as adjunctive therapy. Betaine does raise the methionine level and …