Reduced maternal dexamethasone dosage for the prenatal treatment of congenital adrenal hyperplasia.

MA Coleman, JW Honour - BJOG: An International Journal …, 2004 - search.ebscohost.com
MA Coleman, JW Honour
BJOG: An International Journal of Obstetrics & Gynaecology, 2004search.ebscohost.com
Reduced maternal dexamethasone dosage for the prenatal treatment of congenital adrenal
hyperplasia Page 1 CASE REPORT Reduced maternal dexamethasone dosage for the prenatal
treatment of congenital adrenal hyperplasia MA Coleman a,*, JW Honourb Prenatal treatment of
21-hydroxylase deficiency with dexamethasone has been used since 19841 to prevent virilisation
of the external genitalia of a female with congenital adrenal hyperplasia (CAH). Deficiency of
this enzyme leads to partial or complete failure of conversion of 17-hydroxyprogesterone to …
Abstract
Presents a case of reduced maternal dexamethasone dosage for the prenatal treatment of congenital adrenal hyperplasia. Diagnosis of the patient; Result of the urine steroid analysis; Pregnanediol and oestriol concentrations.
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