Transgenic mouse models for the prevention of breast cancer
Q Shen, PH Brown - … Research/Fundamental and Molecular Mechanisms of …, 2005 - Elsevier
Breast cancer prevention research has made remarkable progress in the past decade. Much
of this progress has come from clinical trials. However, in the future to test the many
promising agents that are now available, pre-clinical models of breast cancer are needed.
Such models are now available. Useful models include rat and mouse models, particularly,
the genetically engineered mice (GEM). Many transgenic mouse models have been
generated by manipulating growth factors and their receptors, cell cycle regulators, signal …
of this progress has come from clinical trials. However, in the future to test the many
promising agents that are now available, pre-clinical models of breast cancer are needed.
Such models are now available. Useful models include rat and mouse models, particularly,
the genetically engineered mice (GEM). Many transgenic mouse models have been
generated by manipulating growth factors and their receptors, cell cycle regulators, signal …
