The origin of urinary angiotensins in humans.
PF Vos, P Boer, B Braam… - Journal of the American …, 1994 - journals.lww.com
To examine whether urinary angiotensin (ANG) I and II excretion responds to changes in
plasma ANG I and ANG II, ANG I or ANG II was infused in seven healthy subjects pretreated
with a 340-mmol sodium diet and 20 mg of enalapril twice daily. Infusion rates were 4, 8, 16,
and 32 pmol/kg per minute for ANG I and 1, 4, and 8 pmol/kg per minute for ANG II. Baseline
ANG I and ANG II excretions averaged 10 and 20 fmol/min, respectively, which is
approximately 0.3 and 5% of the filtered loads. Despite a 20-fold increase in plasma ANG I …
plasma ANG I and ANG II, ANG I or ANG II was infused in seven healthy subjects pretreated
with a 340-mmol sodium diet and 20 mg of enalapril twice daily. Infusion rates were 4, 8, 16,
and 32 pmol/kg per minute for ANG I and 1, 4, and 8 pmol/kg per minute for ANG II. Baseline
ANG I and ANG II excretions averaged 10 and 20 fmol/min, respectively, which is
approximately 0.3 and 5% of the filtered loads. Despite a 20-fold increase in plasma ANG I …
