Functional CD137 receptors are expressed by eosinophils from patients with IgE-mediated allergic responses but not by eosinophils from patients with non–IgE …
IVWM Heinisch, C Bizer, W Volgger… - Journal of allergy and …, 2001 - Elsevier
Background: CD137 (ILA/4-1BB), a member of the TNF/nerve growth factor receptor
superfamily, has previously been suggested to be involved in T-cell activation and
differentiation. Objective: The aim of this study was to investigate expression and potential
function of CD137 in eosinophils. Methods: Eosinophils were isolated from normal control
subjects as well as from patients with bronchial asthma, patients with atopic dermatitis, and
patients with idiopathic eosinophilia. CD137 expression was analyzed by RT-PCR and flow …
superfamily, has previously been suggested to be involved in T-cell activation and
differentiation. Objective: The aim of this study was to investigate expression and potential
function of CD137 in eosinophils. Methods: Eosinophils were isolated from normal control
subjects as well as from patients with bronchial asthma, patients with atopic dermatitis, and
patients with idiopathic eosinophilia. CD137 expression was analyzed by RT-PCR and flow …
